Akira BiotechRegenerative Solutions

EXO-HEP • RESEARCH USE ONLY

Hepatic Exosomes

Derived from stem cells differentiated toward hepatic lineage (human liver stem cell / HLSC–related), carrying liver-specific miRNAs, mRNAs, and proteins.

HLSC-lineage EVs

LIVER-SPECIFIC CARGO

— Differentiated hepatic stem cell exosomes carrying organ-specific miRNAs, mRNAs, and proteins that mirror native hepatocyte/cholangiocyte signaling.

Anti-fibrotic · pro-survival

TARGETED REPAIR

— Delivers anti-inflammatory, anti-fibrotic, and pro-survival RNAs aimed at resolving damaged parenchyma without live-cell transplant risk.

ALF · cirrhosis · NASH

INDICATION MAP

— Covers acute failure, chronic injury, drug/toxin insults, steatohepatitis, genetic iron/copper overloads, autoimmune cholangiopathies, and HCC adjacency research.

ROUTES, FORMATS & APPLICATIONS

Routes

IVIM

Quantities

110 Billion Exosomes

1ml

Potential Applications

Acute Liver Failure (ALF)
Chronic Liver Injury
Drug-Induced Liver Injury
Cirrhosis (fibrosis reversal)
Post-hepatectomy liver regeneration
Fatty Liver Disease
Hemochromatosis
Wilson Disease
Non-alcoholic Steatohepatitis (NASH)
Hepatocellular Carcinoma (HCC)
Autoimmune hepatitis
Primary biliary cholangitis
Primary sclerosing cholangitis
Ischemia-Reperfusion Liver Injury
Chemotherapy-Induced Liver Damage
Liver adhesion formation (post-surgery)
Peritoneal adhesion reduction post-liver surgery

Compliance · Exosomes

cGMP manufacturing & cryopreservation

Cells are manufactured under cGMP conditions and cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

cGMPNON-TOXIC CRYOPRESERVATION>98% VIABILITY

Viability & cryopreservation

Cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

GLUCOSE-BASED CRYO>98% VIABILITY

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