EXO-OST • RESEARCH USE ONLY

Osteoblast Exosomes

Derived from bone-forming osteoblasts; these exosomes contain bone matrix proteins, osteogenic miRNAs, and growth factors such as BMP-2.

BMP-2 · matrix proteins

OSTEOGENIC CARGO

— Bone-lineage EVs packaging matrix proteins, osteogenic miRNAs, and BMP-family growth factors that bias recipient stroma toward mineralized repair.

Remodeling balance

COUPLED ANABOLISM

— Enhances coupled remodeling by supporting osteoblastic anabolism while tempering excessive osteoclastic resorption and local inflammation.

Fracture · graft · jaw

CLINICAL MAP

— Applications span osteoporosis, non-union fractures, segmental defects, post-surgical regeneration, and dental / maxillofacial hard-tissue engineering.

ROUTES, FORMATS & APPLICATIONS

Routes

IVIMSite

Quantities

110 Billion Exosomes

1ml

Potential Applications

Bone Remodeling
Degenerative Bone Disease
Osteoporosis
Bone Resorption Disorders
Bone Fractures
Bone Defects
Post-surgical Bone Regeneration
Dental / Maxillofacial Reconstruction

Compliance · Exosomes

cGMP manufacturing & cryopreservation

Cells are manufactured under cGMP conditions and cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

cGMPNON-TOXIC CRYOPRESERVATION>98% VIABILITY

Viability & cryopreservation

Cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

GLUCOSE-BASED CRYO>98% VIABILITY

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