Akira BiotechRegenerative Solutions

EXO-RPE • RESEARCH USE ONLY

Retinal Pigment Epithelium (RPE) Exosomes

Exosomes derived from RPE cells, enriched in visual cycle regulators and anti-apoptotic factors.

Visual-cycle regulators

RPE-DERIVED CARGO

— EVs enriched for chromophore-handling enzymes and chaperones that keep opsins photosensitive and photoreceptor metabolism in sync.

Photoreceptor survival

NEUROPROTECTION

— Anti-apoptotic and trophic factors that stabilize outer segments, reduce oxidative stress, and temper retinal inflammatory cascades.

Macula · inherited DR

INDICATION MAP

— Applications cluster around AMD, retinitis pigmentosa, Stargardt disease, diabetic retinopathy, glaucoma, and traction/detachment sequelae.

ROUTES, FORMATS & APPLICATIONS

Routes

Eye drops

Quantities

200 Billion Exosomes

2ml

Potential Applications

Age-Related Macular Degeneration (AMD)
Retinitis Pigmentosa
Stargardt Disease
Diabetic Retinopathy
Glaucoma
Retinal detachment
Other retinal degenerative diseases

Compliance · Exosomes

cGMP manufacturing & cryopreservation

Cells are manufactured under cGMP conditions and cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

cGMPNON-TOXIC CRYOPRESERVATION>98% VIABILITY

Viability & cryopreservation

Cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

GLUCOSE-BASED CRYO>98% VIABILITY

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