MSC-HEP • RESEARCH USE ONLY

Hepatic Stem Cells

Designed to mimic liver progenitor cells capable of giving rise to hepatocytes and cholangiocytes. UCT-MSC–derived hepatic stem cells are associated with lower tumorigenic risk relative to some pluripotent approaches.

Hepatocytes · cholangiocytes

BIPOTENT LIVER PROGRAM

— Modeled after liver progenitors that can branch toward parenchymal hepatocytes or bile-duct epithelium for repair-centric indications.

Non-tumorigenic profile

SAFETY VS PLURIPOTENT ROUTES

— Contrasted with iPSC/ESC pathways that carry teratoma concerns — hepatic lineage commitment with documented glucose-based cryo compatibility.

Immune-privileged niche

TRANSPLANTATION BIOLOGY

— Immune-privileged sourcing with derivatives that often retain low immunogenicity — relevant to allogeneic liver regeneration research.

ROUTES, FORMATS & APPLICATIONS

Routes

Quantities

10 Million Cells

2ml

Potential Applications

Acute Liver Failure (ALF)
Chronic Liver Injury
Cirrhosis (fibrosis reversal and regeneration)
Fatty Liver Disease
Hemochromatosis
Wilson Disease
Autoimmune hepatitis
Primary biliary cholangitis
Primary sclerosing cholangitis

Compliance · Stem cells

cGMP manufacturing & cryopreservation

Cells are manufactured under cGMP conditions and cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

cGMPNON-TOXIC CRYOPRESERVATION>98% VIABILITY

Viability & cryopreservation

Cryopreserved using a non-toxic, glucose-based method with greater than 98% viability.

GLUCOSE-BASED CRYO>98% VIABILITY

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