Overview
Overview
Minimally processed UCT Wharton's Jelly containing intact extracellular matrix, MSCs, bioactive proteins, and growth factors — the most complete biological tissue preparation in the Akira Biotech portfolio
FOR RESEARCH USE AND INTERNATIONAL USE ONLY
| Product Configurations |
|---|
| 1 mL / 150 mg cord | 2 mL / 300 mg cord | 3 mL / 75 mg cord diluted with saline |
| cGMP processing |
| Pre-COVID collection |
| All donors first-pregnancy C-section mothers ages 18–29. |
Wharton's Jelly (WJ) is the native gelatinous matrix of the umbilical cord, containing UCT-MSCs embedded in a rich extracellular matrix of hyaluronic acid, collagen I/III/IV/VI, fibronectin, laminin, proteoglycans, and endogenous growth factors. Minimally processed Wharton's Jelly preparations preserve the complete tissue niche — including cell-matrix interactions, matrix-bound growth factors, and the full structural ECM scaffold. This makes WJ particularly effective for applications requiring scaffold-mediated tissue integration (orthopedic, wound healing, surgical augmentation) where the matrix architecture provides additional structural support and growth factor reservoirs beyond what isolated cells or exosomes can deliver.
Components
Key Components
| Component | Therapeutic Function |
|---|---|
| UCT-WJ-MSCs (native) | All MSC paracrine, immunomodulatory, and differentiation capabilities |
| Hyaluronic Acid | Joint lubrication, wound hydration, scaffold structure |
| Collagen I / III / IV / VI | Structural integrity, wound healing scaffolding |
| Fibronectin / Laminin | Cell adhesion matrix; wound healing and tissue integration |
| Proteoglycans (versican, aggrecan) | Matrix water retention, joint lubrication, growth factor binding |
| Matrix-bound VEGF / HGF / IGF-1 | Slow-release growth factor depot from ECM binding |
| Endogenous MSC exosomes | Paracrine signaling vesicles retained in native matrix |
Applications
Therapeutic Applications
- Orthopedic — osteoarthritis, cartilage defects, tendon/ligament repair
- Wound Healing — chronic wounds, burns (scaffold cells)
- Anti-Inflammatory — joint injections, systemic use
- Dental / Oral Surgery — alveolar bone repair, guided tissue regeneration
- Aesthetic / Anti-Aging — facial rejuvenation injections, skin quality
- Spinal Applications — disc augmentation, facet joint support